The bisphosphonate saga
Sunday, November 16th, 2008
This is, apparently, a story without end. Bisphosphonates, in various formulations, dosages, and delivery routes, have been used to build bone density in osteoporosis patients for more than a decade. The efficacy of these drugs has been demonstrated in a number of studies. But like any medication intended for use over a period of many years, questions of the medication?s safety have repeatedly arisen and must be addressed anew. The Food and Drug Administration (FDA), after conducting a review of the latest data, has issued an Early Communication advising health care providers not to alter their prescribing practices and patients not to discontinue their bisphosphonate medication.
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